Taxifolin (Dihydroquercetin)

CAS No. 480-18-2

Taxifolin (Dihydroquercetin)( (+)-Dihydroquercetin )

Catalog No. M14601 CAS No. 480-18-2

Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Taxifolin (Dihydroquercetin)
  • Note
    Research use only, not for human use.
  • Brief Description
    Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
  • Description
    Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.(In Vitro):This is confirmed by the investigation of pure Taxifolin and (+)-Catechin against collagenase activity. Taxifolin exhibits significant inhibitory activity with an IC50 value of 193.3 μM while (+)-Catechin is not active. Taxifolin is a ubiquitous bioactive constituent of foods and herbs. Taxifolin (dihydroquercetin) is a bioactive flavanonol commonly found in grapes, citrus fruits, onions, green tea, olive oil, wine, and many other foods, as well as several herbs (such as milk thistle, French maritime bark, Douglas fir bark, and Smilacis Glabrae Rhizoma).(In Vivo):Taxifolin may be easily metabolized and that its metabolites are the prevalent form in vivo, although limited information is available on metabolism of Taxifolin in vivo.
  • In Vitro
    This is confirmed by the investigation of pure Taxifolin and (+)-Catechin against collagenase activity. Taxifolin exhibits significant inhibitory activity with an IC50 value of 193.3 μM while (+)-Catechin is not active. Taxifolin is a ubiquitous bioactive constituent of foods and herbs. Taxifolin (dihydroquercetin) is a bioactive flavanonol commonly found in grapes, citrus fruits, onions, green tea, olive oil, wine, and many other foods, as well as several herbs (such as milk thistle, French maritime bark, Douglas fir bark, and Smilacis Glabrae Rhizoma).
  • In Vivo
    Taxifolin may be easily metabolized and that its metabolites are the prevalent form in vivo, although limited information is available on metabolism of Taxifolin in vivo.
  • Synonyms
    (+)-Dihydroquercetin
  • Pathway
    Endocrinology/Hormones
  • Target
    Adrenergic Receptor
  • Recptor
    β-adrenergic receptor| TNF-α| Collagenase Tyrosinase| Beta-nerve growth factor| VEGFR2
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    480-18-2
  • Formula Weight
    304.25
  • Molecular Formula
    C15H12O7
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 60 mg/mL (197.2 mM); DMSO: 60 mg/mL (197.2 mM)
  • SMILES
    O=C1[C@H](O)[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
  • Chemical Name
    (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Makena PS, et al. Environ Mol Mutagen, 2009, 50(6), 451-459.
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